The laboratory results did not reveal abnormalities in six patients. The clinical characteristics are summarized in Table 1. The edema extended to the left cervical region over the course of the episode in seven patients. Clinical examination revealed left-sided, non-tender and non-pitting edema of the supraclavicular fossa in all patients. The most frequently reported associated symptoms include a cervical pressure sensation, shortness of breath and general malaise. Physical activity, including jogging and gardening, and warm weather conditions were reported as eliciting factors. The mean duration of episodes in patients with symptom-free intervals was 3.8 days. Seven patients reported having multiple episodes in the past. All episodes had an acute onset of the supraclavicular fossa swelling. Five out of 8 patients were perimenopausal or menopausal at the time of diagnosis. CASE SERIESĪll patients ( n = 8) were female with a mean age of 56 (38–82) at presentation. In this case series, we report on the epidemiology, clinical presentation and imaging findings in the spontaneous cervical swelling syndrome (SCSS). Over the past few years, eight patients consulted our tertiary care facility because of a spontaneous, atraumatic swelling of the left supraclavicular fossa. The pathogenesis remains to be fully elucidated, but a transient obstruction of the thoracic duct is suspected to be the cause, which may account for the extravasation of chyle during the acute event and normalization of lymphatic transport in the in-between episodes. were the first to report on this syndrome as a distinct clinical entity. In the past, several terms have been used to refer to patients with spontaneous, atraumatic swelling of the left supraclavicular fossa, including ‘benign supraclavicular tumorous lymphangiectasia’ and ‘recurrent lymphangiectasia of the left supraclavicular fossa’.
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